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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG2
All Species:
24.85
Human Site:
S622
Identified Species:
42.05
UniProt:
Q9UNQ0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNQ0
NP_004818.2
655
72314
S622
V
K
Q
G
I
D
L
S
P
W
G
L
W
K
N
Chimpanzee
Pan troglodytes
XP_526633
860
94544
S827
V
K
Q
G
I
D
L
S
P
W
G
L
W
K
N
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
S621
A
K
Q
G
I
D
L
S
P
W
G
L
W
K
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMS5
657
72959
S624
I
N
Q
G
I
E
L
S
P
W
G
L
W
K
N
Rat
Rattus norvegicus
Q80W57
657
72942
S624
I
N
Q
G
I
D
L
S
P
W
G
L
W
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510302
654
72378
S621
I
N
Q
G
I
D
L
S
P
W
G
L
W
Q
N
Chicken
Gallus gallus
XP_421638
651
72109
W623
A
P
T
N
M
A
M
W
E
N
I
V
A
L
L
Frog
Xenopus laevis
NP_001091141
661
73548
S628
T
V
Q
G
I
D
Y
S
T
W
G
L
W
Q
N
Zebra Danio
Brachydanio rerio
NP_001036240
643
71395
W615
D
Y
S
A
W
G
L
W
Q
N
H
L
A
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
L657
L
N
F
S
A
A
D
L
P
L
D
Y
V
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
D571
S
A
S
H
K
I
F
D
I
S
I
L
F
G
M
Sea Urchin
Strong. purpuratus
XP_789781
628
69714
Q601
F
S
N
W
D
L
W
Q
N
H
V
A
L
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YS4
751
82913
I719
V
S
I
N
G
M
R
I
D
N
G
L
T
E
V
Baker's Yeast
Sacchar. cerevisiae
P25371
1049
117213
D1022
V
V
Q
N
L
V
F
D
I
K
I
L
A
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
96.6
N.A.
N.A.
81.8
81.4
N.A.
75.8
62.4
68.2
60.9
N.A.
31.5
N.A.
29.6
45
Protein Similarity:
100
75.9
97.7
N.A.
N.A.
89.6
89.1
N.A.
88.2
78.3
82.1
77.8
N.A.
51.6
N.A.
48.4
63.8
P-Site Identity:
100
100
93.3
N.A.
N.A.
80
80
N.A.
80
0
66.6
13.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
20
73.3
13.3
N.A.
13.3
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
8
8
15
0
0
0
0
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
8
43
8
15
8
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% E
% Phe:
8
0
8
0
0
0
15
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
50
8
8
0
0
0
0
58
0
0
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
22
0
8
0
50
8
0
8
15
0
22
0
0
0
0
% I
% Lys:
0
22
0
0
8
0
0
0
0
8
0
0
0
29
0
% K
% Leu:
8
0
0
0
8
8
50
8
0
8
0
79
8
22
15
% L
% Met:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
29
8
22
0
0
0
0
8
22
0
0
0
0
50
% N
% Pro:
0
8
0
0
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
58
0
0
0
0
8
8
0
0
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% R
% Ser:
8
15
15
8
0
0
0
50
0
8
0
0
0
8
0
% S
% Thr:
8
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% T
% Val:
29
15
0
0
0
8
0
0
0
0
8
8
8
0
8
% V
% Trp:
0
0
0
8
8
0
8
15
0
50
0
0
50
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _